The Nelson Mandela foundation called Tutu’s loss “immeasurable.”

“He was larger than life, and for so many in South Africa and around the world his life has been a blessing,” the foundation said in a statement. “His contributions to struggles against injustice, locally and globally, are matched only by the depth of his thinking about the making of liberatory futures for human societies.”

Tutu’s civil and human rights work led to prominent honors from around the world. Former US President Barack Obama awarded him the Presidential Medal of Freedom in 2009. In 2012, Tutu was awarded a $1 million grant by the Mo Ibrahim Foundation for “his lifelong commitment to speaking truth to power.” The following year, he received the Templeton Prize for his “life-long work in advancing spiritual principles such as love and forgiveness which has helped to liberate people around the world.”

Most notably, he received the 1984 Nobel Peace Prize, following in the footsteps of his countryman, Albert Lutuli, who received the prize in 1960.

It was up to the clergy to take the lead in speaking out, said Rev. Frank Chikane, the former head of the South African Council of Churches and a Tutu colleague.

“We reached the stage where the church was a protector of the people, who was the voice for the people,” Chikane told CNN.

The current archbishop of Cape Town and metropolitan of the Anglican Church of Southern Africa, Thabo Makgoba, said that the church will plan Tutu’s funeral and memorial services.

“Desmond Tutu’s legacy is moral strength, moral courage and clarity,” Makgoba said in a statement. “He felt with the people. In public and alone, he cried because he felt people’s pain. And he laughed — no, not just laughed, he cackled with delight when he shared their joy.”

In Britain, Prime Minister Boris Johnson and Archbishop of Canterbury Justin Welby issued statements praising Tutu for his sagacity and infectious positivity.

“(He) will be remembered for his spiritual leadership and irrepressible good humor,” Johnson said.

Welby called Tutu “a prophet and priest, a man of words and action — one who embodied the hope and joy that were the foundations of his life.”

“Even in our profound sorrow we give thanks for a life so well lived,” he said.

The path was rocky

In the 1950s, Tutu had resigned as a teacher in protest of government restrictions on education for Black children, the Bantu Education Act. He was ordained in 1960 and spent the ’60s and early ’70s alternating between London and South Africa. In 1975 he was appointed dean of St. Mary’s Cathedral in Johannesburg and immediately used his new position to make political statements.

It wasn’t a plan, though from an early age he’d been inspired by Trevor Huddleston, a priest and early anti-apartheid activist who worked in a Johannesburg slum in the 1950s. By embarking on this path, he inspired thousands of his countrymen — and more around the world.

Tutu believed he didn’t have a choice, even if the path was rocky.

“I really would get mad with God. I would say, ‘I mean, how in the name of everything that is good can you allow this or that to happen?’ ” he told the Academy of Achievement. “But I didn’t doubt that ultimately good, right, justice would prevail.”

Tumultuous times

Desmond Mpilo Tutu was born October 7, 1931, in Klerksdorp, a town in South Africa’s Transvaal province. His father was a teacher and his mother was a domestic worker, and young Tutu had plans to become a doctor, partly thanks to a boyhood bout of tuberculosis, which put him in the hospital for more than a year. He even qualified for medical school, he said.

But his parents couldn’t afford the fees, so teaching beckoned.

“The government was giving scholarships for people who wanted to become teachers,” he told the Academy of Achievement. “I became a teacher and I haven’t regretted that.”

However, he was horrified at the state of Black South African schools, and even more horrified when the Bantu Education Act was passed in 1953 that racially segregated the nation’s education system. He resigned in protest. Not long after, the Bishop of Johannesburg agreed to accept him for the priesthood — Tutu believed it was because he was a Black man with a university education, a rarity in the 1950s — and took up his new vocation.  

The 1960s and 1970s were tumultuous times in South Africa. In March 1960, 69 people were killed in the Sharpeville Massacre, when South African police opened fire on a crowd of protesters. Lutuli, an ANC leader who preached non-violence, was awarded the Nobel Peace Prize later that year — while banned from leaving the country. (The government finally let him go for a few days to accept his prize.)

Mandela — then a firebrand leading an armed wing of the ANC — was arrested, tried and, in 1964, sentenced to life in prison. In the early ’70s, the government forced millions of Black people to settle in what were called “homelands.”

Tutu spent many of these years in Great Britain, watching from afar, but finally returned for good in 1975, when he was appointed dean of St. Mary’s Cathedral in Johannesburg. The next year he was consecrated Bishop of Lesotho. He gained renown for a May 1976 letter he wrote to the prime minister, warning of unrest.

“The mood in the townships was frightening,” he told the Academy of Achievement.

A month later Soweto exploded in violence. More than 600 died in the uprising.

A distinctive figure

As the government became increasingly oppressive — detaining Black people, establishing onerous laws — Tutu became increasingly outspoken.

“He was one of the most hated people, particularly by White South Africa, because of the stance he took,” former Truth and Reconciliation Commission member Alex Boraine told CNN.

Added Chikane, the South African Council of Churches colleague, “His moral authority (was) both his weapon and his shield, enabling him to confront his oppressors with a rare impunity.”

With his scarlet vestments, Tutu cut a distinctive figure as he preached from the bully pulpit — perhaps never more so than in his Nobel Prize speech in 1984.

Four years later, in 1994, Mandela would be elected president. Tutu compared being allowed to vote for the first time to “falling in love” and said — behind the birth of his first child — introducing Mandela as the country’s new president was the greatest moment of his life.

Controversial stances

Tutu’s work was not done, however. In 1995 Mandela appointed him chair of the Truth and Reconciliation Commission to address the human rights violations of the apartheid years. Tutu broke down at the TRC’s first hearing in 1996.

The TRC gave its report to the government in 1998. Tutu established the Desmond Tutu Peace Trust the same year.

He returned to teaching, becoming a visiting professor at Emory University in Atlanta for two years and later lecturing at the Episcopal Divinity School in Cambridge, Massachusetts. He published a handful of books, including “No Future Without Forgiveness” (1999), “God Is Not a Christian” (2011), and a children’s book, “Desmond and the Very Mean Word” (2012).

But he was also distinguished for his sense of humor, embodied in a distinctive, giggle-like laugh.

Despite all the praise and fame, however, he told CNN he didn’t feel like a “great man.”

“What is a great man?” he said. “I just know that I’ve had incredible, incredible opportunities. … When you stand out in a crowd, it is always only because you are being carried on the shoulders of others.”

For all of his good works, he added, there may have been another reason he had so many followers.

“They took me only because I have this large nose,” he said. “And I have this easy name, Tutu.”

Tutu is survived by his wife of more than 60 years, Nomalizo Leah Tutu, with whom he had four children, Trevor, Theresa, Naomi and Mpho.